| FISH Parameters |
| Target Diseases |
Classfication |
Tests Parameters |
Chromosome Aberration |
Material |
Preservation |
Needed
Time * |
Container |
| CML |
Blood Disease |
Major-BCR/ABL |
t(9;22) |
Blood 3ml
Bone Marrow Aspirate 0.5ml |
Cold Strage |
Within 10days |
Containing Heparin Na
Container |
| AML(M2) |
ETO/AML-1 |
t(8;21) |
| AML(M3) |
PML/RARA |
t(15;17) |
| B-CLL |
D13S25 |
13q14.3 |
| CLL/MM |
D13S319 |
13q14.3 |
| MM |
FGFR3/IgH |
t(4:14) |
| MM |
IgH/MAF |
t(4;16) |
| ALL NHL |
MYC/IgH |
t(8;14) |
| ALL NHL |
IgH/CCND1 |
t(11;14) |
| NHL |
IgH/BCL2 |
t(11;14) |
| ALL |
TEL/AML1 |
t(12;21) |
| MDS,AML |
EGR-1 |
5q31 |
| AML |
CBFB |
inv(16)(p13q22) |
| AML |
MLL |
t(11q23) |
| AML |
CSFIR |
5q33-q34 |
| AML |
p16 |
9p21 |
| NHL |
BCL6 |
t(3q27) |
| Prader-Willi syndrome |
Congenital Anomaly |
Prader-Willi syndrome
(SNRPN) |
15q11-13 |
Blood 3ml
Paraffin Sample |
Cold Strage |
Within 10days |
Containing Heparin Na
Container |
Prader-Willi syndrome
(GABRB3) |
15q11-13 |
Prader-Willi syndrome
(D15S10) |
15q11-13 |
Prader-Willi syndrome
(D15S11) |
15q11-13 |
| Angelman syndrome |
Angelman syndrome
(SNRPN) |
15q11-13 |
Angelman syndrome
(GABRB3) |
15q11-13 |
Angelman syndrome
(D15S10) |
15q11-13 |
Angelman syndrome
(D15S11) |
15q11-13 |
DiGeorge/VCFS
CATCH22 |
DiGeorge/VCFS
region(CATCH22) |
22q11.2 |
| William syndrome |
William syndrome |
7q11.23 |
| Cat cry syndrome |
Cat cry syndrome |
5p15.2 |
| Miller-Dieker syndrome |
Miller-Dieker syndrome |
17p13.3 |
| Cancer-related |
Cancer-related |
p53 |
17p131 |
| Breast Cancer, Ovarian Cancer |
C-MYC |
8q24.2-24.3 |
| Breast Cancer, others. |
Cyclin D1 |
11q13 |
Blood |
| Retinoblastoma gene locus |
Retinoblastoma gene locus |
13q14 |
Bone Marrow Aspirate |
Container with
culture fluid |
| Prostate Cancer |
N-MYC |
2p23-24 |
Tissue |
| Breast Cancer, Others |
HER-2/nue |
17q11.2-q12 |
Paraffin Sample |
|
Within 20days |
|
|
Autosomal Chromosome Anomaly |
Chromosome 1 |
D1Z1 |
Blood 3ml
Bone Marrow Aspirate 0.5ml |
Cold Starge |
Within 10days |
Containing Heparin Na
Container |
|
Chromosome 1 |
D1Z5 |
|
Chromosome 2 |
D2Z1 |
|
chromsome 3 |
D3Z1 |
| AML(M2,M4),B-ALL |
Chromosome 4 |
D4Z1 |
| MDS,AML |
Chromosome 5 |
5q31 |
|
Chromosome 6 |
D6Z1 |
| MDS,AML |
Chromosome 7 |
D7Z1 |
| MDS,AML |
Chromosome 8 |
D8Z2 |
|
Chromosome 9 |
D9Z1 |
|
Chromosome 10 |
D10Z1 |
| MDS,AML |
Chromosome 11 |
D11Z1 |
|
Chromosome 12 |
D12Z1 |
| Patau syndrome,RB1,CLL |
Chromosome 13 |
13q14 |
|
Chromosome 15 |
13q14 |
|
Chromosome 16 |
D16Z3 |
| MDS,AML |
Chromosome 17 |
D17Z1 |
| Edwards syndrome |
Chromosome 18 |
D18Z1 |
| MDS,AML |
Chromosome 19 |
Whole painting |
|
Chromosome 20 |
D20Z1 |
| Down syndrome.AML |
Chromosome 21 |
21q22.13-q22.2 |
| AML |
Chromosome 22 |
22q11.2 |
Turner syndrome
Klinefelter syndrome |
Sex Chromosome Aberration |
XY Chromosome |
DXZ1
DYZ3 |
Blood 3ml
Bone Marrow Aspirate 0.5ml
Paraffin Sample |
Cold Strage |
Within 10days |
Containing Heparin NA
Container |
|
Y Chromosome(DYZ1) |
DYZ1 |
| Y Chromosome(DYZ3) |
DYZ3 |
| Y Chromosome(SRY) |
Yp11.3 |
| Sperm XY |
DXZ1/DYZ3 |
|
Patau syndrome
Down syndrome
Edwards syndrome |
|
PGT-1 |
#13
#18
#21 |
Amniotic Fluid
others |
Cold Strage |
Within 10days |
Containing Heparin NA
Container |
| Bladder Cancer, Otehrs |
UROVYSION |
#3
#7
#17
p16 |
Urine
Paraffin Sample
Others |
| Identification of Marker Chromosome |
|
M-FISH (Multiplex-FISH) |
1-22.X.Y |
Blood 3ml
Bone Marrow Aspirate 0.5ml |
Cold Starge |
Within 14days |
Containing Heparin NA
Container |
|
| *Case in Japan. |
| |
 |
